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Allele : Tg(Ucp1-cre/ERT2)426Biat transgene insertion 426, Biomodels Austria

Primary Identifier  MGI:5498561 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Ucp1-cre/ERT2)426Biat
Strain of Origin  C57BL/6N Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  Sequences encoding a cre/ERT2 fusion protein, Frt-flanked neo cassette, and a polyadenylation signal were inserted into a BAC containing the Ucp1 promoter by recombineering methods. The neo marker was not removed, as the original construct showed more efficient cre activity. The purified construct was microinjected into fertilized C57BL/6N oocytes. Line 426 was established.
  • mutations:
  • Insertion
  • synonyms:
  • Ucp1-CreER,
  • Ucp1-CreER
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

32 Publication categories