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Allele : Arhgef26<tm1.1Kbur> Rho guanine nucleotide exchange factor 26; targeted mutation 1.1, Keith Burridge

Primary Identifier  MGI:5500046 Allele Type  Targeted
Attribute String  Null/knockout Gene  Arhgef26
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance (neo) cassette with a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exon 4, exon 5 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the liver, lung and brain.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories