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Allele : Hoxb8<em1(cre)Mrc> homeobox B8; endonuclease-mediated mutation 1, Mario R Capecchi
Primary Identifier  MGI:7855742 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s), Recombinase Gene  Hoxb8
Strain of Origin  Not Specified Is Recombinase  true
Is Wild Type  false
molecularNote  These mice were generated from Hoxb8tm2.1(cre)Mrc using CRISPR/Cas9 genome editing technology to replace the sequences encoding the wild-type homeodomain DNA-binding site of Hoxb8 (I192-WFQNR198R) with the low DNA-affinity sequence AEFAAAA.
  • mutations:
  • Insertion
  • synonyms:
  • Hoxb8<mut-IRES-Cre>,
  • Hoxb8<mut-IRES-Cre>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

Trail: Allele

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Trail: Allele




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