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Allele : Prkab1<tm1b(KOMP)Wtsi> protein kinase, AMP-activated, beta 1 non-catalytic subunit; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5501071 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Prkab1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_gt0 cassette was inserted at position 116159303 of Chromosome 5 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site was inserted downstream of the targeted exon(s) at position 116160137. The critical exon(s) were thus flanked by loxP sites, and subsequent Cre-mediated excision removed the critical sequence and neomycin selection cassette yielding a reporter knockout allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Prkab1<tm1b>,
  • Prkab1<tm1b>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

11 Carried By

0 Driven By

10 Publication categories