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Allele : Tg(LRRK2*G2019S)2AMjff transgene insertion 2A, The Michael J Fox Foundation

Primary Identifier  MGI:5502368 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(LRRK2*G2019S)2AMjff
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  A 188 kb bacterial artificial chromosome (BAC) containing the entire human LRRK2 (leucine-rich repeat kinase 2) gene was modified by targeted mutation of the LRRK2 locus to harbor the LRRK2 G2019S mutation associated with autosomal dominant, late-onset Parkinson's disease originally identified in Spanish families originating from the Basque region.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Tg(LRRK2*G2019S)2AGrsr,
  • Tg(LRRK2*G2019S)2AGrsr
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

15 Publication categories