Primary Identifier | MGI:5502368 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(LRRK2*G2019S)2AMjff |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 188 kb bacterial artificial chromosome (BAC) containing the entire human LRRK2 (leucine-rich repeat kinase 2) gene was modified by targeted mutation of the LRRK2 locus to harbor the LRRK2 G2019S mutation associated with autosomal dominant, late-onset Parkinson's disease originally identified in Spanish families originating from the Basque region. |