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Allele : Hsd11b1<tm1Lex> hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Lexicon Genetics

Primary Identifier  MGI:5502586 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Hsd11b1
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
molecularNote  A lacZ/neomycin resistance cassette replaced exons 4 and 5. QRT-PCR confirmed the absence of transcript expression in the liver, adipose, spleen and macrophage.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories