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Allele : Igh<tm2.1(4E10)Nemz> immunoglobulin heavy chain complex; targeted mutation 2.1, David Nemazee
Primary Identifier  MGI:5505305 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Igh
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette replaced the DQ52-JH cluster in the Igh gene with HIV antibody 4E10 variable region coding sequence. Cre-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • 4E10H,
  • 4E10H
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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