Primary Identifier | MGI:5504508 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Shox2 |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A targeting vector introduced the cre recombinase coding sequence and an frt-flanked PGK-neo selection cassette into the Shox2 locus via homologous recombination in ES cells, replacing exon 1, intron 1 and part of exon 2. Germline animals were crossed to Flp deleter mice to remove the PGK-neo cassette. |