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Allele : Prx<tm2.1Brp> periaxin; targeted mutation 2.1, Peter Brophy

Primary Identifier	MGI:5509222	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Prx
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 5, which encodes the PDZ domain. A floxed neomycin resistance cassette was inserted downstream of exon 5. Cre-mediated recombination removed the neomycin resistance cassette and left exon 5 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Prx<fl>,
Prx<fl>

earliestPublication:
Wu LM, et al. (2012) Increasing internodal distance in myelinated nerves accelerates nerve conduction to a flat maximum. Curr Biol 22(20):1957-61

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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