| Primary Identifier | MGI:5508897 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Magi2 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A genomic fragment of exon 4 (transcript variant 1) was replaced with a neomycin resistance cassette. Exon 4 encodes a portion of the GUK domain common to all three protein isoforms. Western blot and qRT-PCR analysis performed on brain protein lysates and RNA confirmed the loss of protein and mRNA transcript expression in homozygous mutant mice. |
