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Allele : Mmp19<tm1Rase> matrix metallopeptidase 19; targeted mutation 1, Radislav Sedlacek

Primary Identifier  MGI:5509300 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mmp19
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The catalytic domain of Mmp19 (1088 bp region spanning the end of exon 3 and whole of exon 4) was replaced with a neoR cassette oriented in the opposite direction to the endogenous Mmp19. Immunoblotting and immunohistochemistry confirmed absence of MMP19 protein in cell lysates and in skin, respectively.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

6 Publication categories