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Allele : Tg(T-cre/ERT2)1Lwd transgene insertion 1, Mark Lewandoski

Primary Identifier  MGI:5509185 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(T-cre/ERT2)1Lwd
Strain of Origin  (C57BL/6NCr x C3H/HeNCr)F2 Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
description  Zygotes for injection were derived by intercrossing B6C3F1 (C57BL/6NCr X C3H/HeNCrMTV) mice.
molecularNote  The cre recombinase coding region fused to the sequence for a mutated ligand-binding domain of the human estrogen receptor was inserted into a construct where it is under the control of the 500 bp brachyury (T) promoter. Eight transgenic lines were generated and one showed extensive cre activity in presence of tamoxifen but little without tamoxifen induction.
  • mutations:
  • Insertion
  • synonyms:
  • TCreERT2,
  • TCreERT2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

10 Publication categories