Primary Identifier | MGI:5510143 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Kit |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A single point mutation deleting valine 558 was introduced to exon 11 and a floxed neomycin resistance cassette was introduced to intron 11 via homologous recombination. Cre-mediated recombination removed the neomycin resistance cassette. |