Primary Identifier | MGI:5510964 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Fzd3 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The following elements were inserted into the mouse Fzd3 (frizzled homolog 3 (Drosophila)) locus via homologous recombination: a loxP site in intron 2, a 3HA (hemagglutinin) epitope in the coding region between the cysteine-rich domain and the first transmembrane domain, a loxP site in intron 3, and an Frt-flanked PGK-neo cassette. The neomycin cassette was removed by germline Flp-mediated recombination. |