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Allele : Braf<tm2.1Urr> Braf transforming gene; targeted mutation 2.1, Urr R Rapp

Primary Identifier	MGI:5512688	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Braf
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neomycin resistance cassette and left exon 3 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
BRaf<fl>,
BRaf<fl>

earliestPublication:
Pfeiffer V, et al. (2013) Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum. PLoS One 8(3):e58259

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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