| Primary Identifier | MGI:5512689 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Braf |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the neomycin resistance cassette. Western blot analysis confirmed the absence of the two predicted protein isoform expression in embryos. This allele is predicted to produce a truncated, non-functional protein. |
