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Allele : Gt(ROSA)26Sor<tm1.1Ksvo> gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Karel Svoboda
Primary Identifier  MGI:5512720 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, No functional change, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to contain a CAG promoter, followed by a loxP-STOP-LoxP (LSL) sequence and an H2B-mCherry fusion protein (coding sequence for the human HIST1H2BB gene [histone 1 H2bb] followed C-terminally by Enhanced Red Fluorescent Protein gene) An AttB-PGKNeo-AttP cassette was placed downstream of the H2B-mCherry fusion protein. This entire construct was inserted into the Gt(ROSA)26Sor locus. PhiC31-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26-LSL-H2B-mCherry,
  • Rosa26-LSL-H2B-mCherry
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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