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Allele : Pax6<tm2(Pax6_i5a,Pax2)Xzh> paired box 6; targeted mutation 2, Xin Zhang

Primary Identifier  MGI:5512910 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Pax6
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The coding sequence (exons 4 through 13) was replaced with a loxP site, cDNA encoding an alternatively spliced isoform for Pax6 that contains 14 amino acid inserted within the PD domain that changed its DNA binding specificity (5a), an FRT-flanked neomycin resistance/STOP cassette, loxP site and cDNA encoding Pax2. This allele expressed the 5a isoform of Pax6 (Pax6_i5a).
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pax6<5a>,
  • Pax6<5a>
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories