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Allele : Rad50<tm3.1Flv> RAD50 double strand break repair protein; targeted mutation 3.1, Richard A Flavell

Primary Identifier	MGI:5514423	Allele Type	Targeted
Gene	Rad50	Transmission	Germline
Strain of Origin	129S6/SvEvTac	Is Recombinase	false
Is Wild Type	false

molecularNote

A floxed neomycin resistance (neo) cassette replaced DNaseI hypersensitive sites 4 and 5. Cre-mediated recombination removed the neo cassette. Western blot analysis confirmed normal protein expression.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
RHS4,5,
RHS4,5,
RHS45,
RHS45

earliestPublication:
Williams A, et al. (2013) Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression. Proc Natl Acad Sci U S A 110(17):6955-60

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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