Primary Identifier | MGI:5515767 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Myo1c |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon E-1. A floxed neomycin resistance cassette was inserted downstream of exon E-1. Cre-mediated recombination removed exon E-1 and the neomycin resistance cassette. Western blot analysis confirmed the absence of nuclear Myo1c protein expression. |