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Allele : Slc6a2<tm1.1Mkh> solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; targeted mutation 1.1, Maureen K Hahn

Primary Identifier  MGI:5516082 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Slc6a2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 9 was replaced with a modified one in which a G to C point mutation results in the amino acid substitution of proline for alanine at position 457 (A457P), mimicking a mutation found in some postural orthostatic tachycardia syndrome (POTS) patients. A self-excising neomycin resistance cassette removed itself from the final allele.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • NET<P>,
  • NET<P>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories