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Allele : Tg(Prnp-ATXN3*70Q)70.61Olri transgene insertion 70.61, Olaf Riess

Primary Identifier  MGI:5516451 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Prnp-ATXN3*70Q)70.61Olri
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  The mouse prion promoter (containing 1140 bp of the prion protein gene upstream of exon 1, the complete exon 1, intron 1, and the first 52 bp of exon 2) drives the expression of the full-length human ATAXIN-3 (ATAXIN-3c isoform that contains an additional ubiquitin-interacting motif at its C terminus) containing 70 CAG repeats. Four lines were created: 70.42, 70.48, 70.61, and 70.66.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories