| Primary Identifier | MGI:5521582 | Allele Type | Targeted |
| Attribute String | Constitutively active | Gene | Tgm2 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 11 was replaced with a modified exon 11 in which nucleotide substitutions (AGA to GCC) result in the amino acid substitution of alanine for arginine at position 579 (R579A). This mutation results in a constitutively active protein. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the modified exon 11. |
