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Allele : Mbnl3<tm1.1Sws> muscleblind like splicing factor 3; targeted mutation 1.1, Maurice S Swanson

Primary Identifier  MGI:5518844 Allele Type  Targeted
Attribute String  Hypomorph, Modified isoform(s) Gene  Mbnl3
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 2. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination remove exon 2 and the neomycin resistance cassette. Western blot analysis confirmed the absence of exon 2-containing isoform(s) but over-expression of isoform ZnF3/4 in the E15 forelimb.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mbnl3<deltaE2>,
  • Mbnl3<deltaE2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories