| Primary Identifier | MGI:5523519 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hat1 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 3. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the neomycin resistance cassette. The predicted product of this allele lacks the entire active site. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. |
