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Allele : Cers6<tm1.1Kwi> ceramide synthase 6; targeted mutation 1.1, Klaus Willecke

Primary Identifier  MGI:5523623 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cers6
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  111 bp of the coding region of the catalytically active exon 7 was replaced with a STOP codon, IRES sequence, lacZ reporter gene and FRT flanked neomycin resistance cassette. Flp-mediated recombination removed the neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the cerebellum and forebrain.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele