Primary Identifier | MGI:5523623 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Cers6 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 111 bp of the coding region of the catalytically active exon 7 was replaced with a STOP codon, IRES sequence, lacZ reporter gene and FRT flanked neomycin resistance cassette. Flp-mediated recombination removed the neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the cerebellum and forebrain. |