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Allele : Fbxw7<tm2Iaai> F-box and WD-40 domain protein 7; targeted mutation 2, Iannis Aifantis
Primary Identifier  MGI:5524152 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Fbxw7
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 11 was replaced with a floxed neomycin resistance cassette and a modified exon 11 in which nucleotide substitutions (CGG to TGC) result in the amino acid substitution of cysteine for arginine at position 468 (R468C).
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Fbxw7<R468Neo>,
  • Fbxw7<R468Neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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