| Primary Identifier | MGI:5524988 | Allele Type | Targeted |
| Gene | Itgb2 | Transmission | Germline |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 16 was replaced with a modified one in which nucleotide substitutions result in the amino acid substitution of alanine for threonine at positions 759, 760 and 761 (T759A, T760A, T761A). These mutations abolish Fermt3 (Kindlin 3) binding but did not affect talin binding. Flp-mediated recombination removed the F3-flanked puromycin resistance cassette inserted upstream of exon 15. |
