| Primary Identifier | MGI:5527371 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Tg(Aire-cre/ERT2*)1Mand |
| Strain of Origin | FVB/N | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A targeting construct was used for recombineering to insert an ERT2-cre-ERT2 sequence (cre fused to two mutated human estrogen receptor ligand-binding domains) into a BAC containing the Aire locus. The inducible cre cassette replaced exon 2 of Aire. The resulting linearized BAC was injected into fertilized FVB oocytes. Founder and line number information is not available. |
