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Allele : Tnfaip3<tm3.1Ama> tumor necrosis factor, alpha-induced protein 3; targeted mutation 3.1, Averil Ma
Primary Identifier  MGI:5528684 Allele Type  Targeted
Attribute String  Not Specified Gene  Tnfaip3
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette was inserted upstream of exon 3. Exon 3 was replaced with one in which a nucleotide substitution(s) results(s) in the amino acid substitution of alanine for cysteine at position 103 (C103A). This mutation disrupts the deubiquitinating function of the OTU domain. Cre-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Tnfaip3<OTU>,
  • Tnfaip3<OTU>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories





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