| Primary Identifier | MGI:5543257 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Samhd1 |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6J)F1 |
| Is Recombinase | false | Is Wild Type | false |
| description | This allele was generated but not maintained. |
| molecularNote | A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2. Flp-mediated recombination removed the neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in bone marrow-derived dendritic cells and mouse embryonic fibroblasts. |
