Primary Identifier | MGI:5543604 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Car7 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neomycin resistance cassette inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 7. Cre-mediated recombination removed the neomycin resistance cassette and exons 5 through 7. Western blot analysis confirmed the absence of protein expression in the hippocampus. |