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Allele : Tg(Amh-SMAD2*)#Jebu transgene insertion, Joanna E Burdette

Primary Identifier  MGI:5543909 Allele Type  Transgenic
Attribute String  Dominant negative, Inserted expressed sequence Gene  Tg(Amh-SMAD2*)#Jebu
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a mouse minimal Mullerian-inhibiting substance promoter (-180 bp), an epitope Flag tag, a C-terminal truncation of the human Smad2 gene resulting in a dominant negative effect, and a human GH polyadenylation sequence. The Amh promoter drives transgene expression in testicular Sertoli cells and ovarian granulosa cells.
  • mutations:
  • Insertion
  • synonyms:
  • Smad2DN,
  • Smad2DN
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele