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Allele : Ryr1<tm2.1Itl> ryanodine receptor 1, skeletal muscle; targeted mutation 2.1, inGenious Targeting Laboratory
Primary Identifier  MGI:5544310 Allele Type  Targeted
Gene  Ryr1 Transmission  Germline
Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitution(s) result(s) in the amino acid substitution of alanine for serine at position 2844 (S2844A). This amino acid substitution blocks phosphorylation at this site. Cre-mediated recombination removed the floxed neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • RyR1-S2844A,
  • RyR1-S2844A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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