| Primary Identifier | MGI:5538732 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ikbkg |
| Transmission | Germline | Strain of Origin | (C57BL/6NTac x 129S6/SvEvTac)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 2 through 5 were replaced with a N-terminally Myc-tagged cDNA containing nucleotide substitutions that result in the amino acid substitution of arginine for lysine at positions 285 and 399 (K285R, K399R). Flp-mediated recombination removed an FRT- and loxP-flanked neomycin resistance cassette inserted downstream of the inserted cDNA. The protein product is nonubiquitinatable and phenotypic analysis indicates a null allele. |
