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Allele : Tgfbr2<tm1.1Hcd> transforming growth factor, beta receptor II; targeted mutation 1.1, Harry C Dietz
Primary Identifier  MGI:5543796 Allele Type  Targeted
Gene  Tgfbr2 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Site-directed mutagenesis was performed to substitute glycine 358 with tryptophan (GGC->TGG; guanine to thymine and cytosine to guanine at nucleotides 1069 and 1071 respectively) in exon 4 of the targeted gene. A loxP-flanked neomycin selection cassette was placed in intron 3. Cre-mediated recombination removed the floxed neo cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Tgfbr2<G357W>,
  • Tgfbr2<G357W>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

6 Publication categories





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