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Allele : Gt(ROSA)26Sor<tm2(tTA,CMV*1-KIAA1549/BRAF,-EGFP)Gtm> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, David H Gutmann
Primary Identifier  MGI:5543802 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter, Transactivator Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector introduced into the locus a floxed neomycin resistance/STOP cassette, tetracycline-regulated transcription activator (tTA), insulator, hCMV*1 promoter, intron, fusion of human KIAA1549 (exons 1 to 16) and BRAF (exons 9 to 18) (KIAA:BRAF 16_9), IRES and EGFP. This fusion was found in pilocytic astrocytomas of young children.
  • mutations:
  • Insertion
  • synonyms:
  • LSL-KIAA1549:BRAF,
  • LSL-KIAA1549:BRAF,
  • LSL-f-BRAF,
  • LSL-f-BRAF
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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