| Primary Identifier | MGI:5547613 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Prdm4 |
| Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The EUCOMM targeting vector (project ID 45696) introduced an FRT site, lacZ gene, loxP site, neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site upstream of exon 6. A third loxP site was inserted downstream of exon 7. Exons 6 and 7 correspond to the PR/SET domain. Cre-mediated recombination removed the neomycin resistance cassette and exons 6 and 7, leaving the lacZ reporter intact. |
