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Allele : Tg(Cga-icre)961Sac transgene insertion 961, Sally A Camper
Primary Identifier  MGI:5547616 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Cga-icre)961Sac
Strain of Origin  C57BL/6J x (C57BL/6 x DBA/2)F1 Is Recombinase  true
Is Wild Type  false
molecularNote  A BAC (RP24-329P6) containing the Cga (alphaGSU) gene was modified by inserting a cassette composed of the sequence encoding a mammalian codon usage optimized cre recombinase (icre) and an Frt-flanked kanamycin selection marker, replacing the start codon in exon 2 of Cga with the ATG initiation codon of cre. Flpe excision removed the kanamycin selection marker. The modified BAC was injected into pronuclei of fertilized oocytes to generate transgenic mice. Line 961 was established.
  • mutations:
  • Insertion
  • synonyms:
  • alphaGSU-iCre,
  • alphaGSU-iCre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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1 Driven By

4 Publication categories





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