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Allele : Nme8<tm1.1Arte> NME/NM23 family member 8; targeted mutation 1.1, TaconicArtemis

Primary Identifier	MGI:5550546	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Nme8
Transmission	Germline	Strain of Origin	C57BL/6NTac
Is Recombinase	false	Is Wild Type	false

molecularNote

The conserved WCGPC site in exon 4 was mutated to WSGPS. An FRT flanked neo-cassette was inserted downstream of exon 4 and then removed via recombinase, resulting in a single FRT site in intron 4.

mutations:
Nucleotide substitutions,
Insertion

cellLines:
Not Specified

synonyms:
Sptrx-2<->,
Sptrx-2<->

earliestPublication:
Smith TB, et al. (2013) Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress. Free Radic Biol Med 65:872-81

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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