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Allele : Mycl<tm1.1Kmm> v-myc avian myelocytomatosis viral oncogene lung carcinoma derived; targeted mutation 1.1, Kenneth Murphy

Primary Identifier  MGI:5550274 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mycl
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was designed to replace the first coding exon with a green fluorescent protein (GFP) sequence and a loxP-flanked neomycin resistance (neo) cassette. Mutant mice were bred with Tg(CMV-cre)1Cgn mice (on a C57BL/6 congenic background) to remove the neo selection cassette. qPCR failed to detect mRNA in mutants. GFP expression is detected in dendritic cells in both lymphoid and non-lymphoid peripheral tissues.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mycl1<gfp>,
  • Mycl1<gfp>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

7 Publication categories