Primary Identifier | MGI:5550468 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Ucp1-cre)1Evdr |
Strain of Origin | FVB | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The C57BL/6 mouse bacterial artificial chromosome (BAC) 148M1 containing the entire Ucp1 gene, and other genes, was modified by inserting sequence encoding cre recombinase, into the translation initiation site into exon 1 of the Ucp1 gene. An FRT site flanked KAN cassette and a loxP site were removed. DNA from the modified BAC clone was used as the source for the transgene, which was microinjected into the pronucleus of FVB fertilized eggs. A founder line was subsequently established. |