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Allele : Clp1<tm1.1Pngr> CLP1, cleavage and polyadenylation factor I subunit; targeted mutation 1.1, Josef M Penninger
Primary Identifier  MGI:5554792 Allele Type  Targeted
Attribute String  Not Specified Gene  Clp1
Transmission  Germline Strain of Origin  (C57BL/6 x 129P2/OlaHsd)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of a modified exon 2 in which nucleotide substitutions (AAG to GCG) results in the amino acid substitution of alanine for lysine at position 127 (K127A). Flp-mediated recombination removed the FRT- and loxP-flanked neomycin resistance cassette inserted downstream of the modified exon 2. The product of this allele is predicted to be a kinase dead form.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Clp1<K127A>,
  • Clp1<K>,
  • Clp1<K127A>,
  • Clp1<K>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

6 Publication categories





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