Primary Identifier | MGI:5556106 | Allele Type | Targeted |
Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed stop cassette followed by a cDNA fragment encoding the mouse Notch3 intracellular domain (amino acids 1668 to 2318), IRES and sequence for YFP were inserted into intron 1. The Notch3 fragment acts as a constitutively active receptor. |