|  Help  |  About  |  Contact Us

Allele : Slx1b<tm1.1Jrou> SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae); targeted mutation 1.1, John Rouse

Primary Identifier  MGI:5559221 Allele Type  Targeted
Attribute String  Null/knockout Gene  Slx1b
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette with an IRES and a 5' loxP site was inserted upstream of the coding sequence in exon 1. An additional loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the coding sequence in exon 1 and the selection cassette. Western blot analysis confirmed the absence of protein expression in testis and mouse embryonic fibroblasts.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories