| Primary Identifier | MGI:7568815 | Allele Type | Endonuclease-mediated |
| Gene | Gdf11 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Aspartic acid codon 385 (GAC) in exon 3 was changed to glycine (GGC) (p.D385G) and glutamine codon 387 (CAG) to glutamic acid (GAG) (p.Q387E) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations change the endogenous amino acids in the encoded peptide to their equivalents from paralog Mstn. |
