|  Help  |  About  |  Contact Us

Allele : Mstn<em1Rlee> myostatin; endonuclease-mediated mutation 1, Richard T Lee

Primary Identifier  MGI:7568816 Allele Type  Endonuclease-mediated
Gene  Mstn Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Glycine codon 356 (GGC) in exon 3 was changed to aspartic acid (GAC) (p.G356D) and glutamic acid codon 358 (GAA) to glutamine (CAA) (p.E358Q) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations change the endogenous amino acids in the encoded peptide to their equivalents from paralog Gdf11.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Gdf8<11aa>,
  • Gdf8<Gdf11aa>,
  • Gdf8<11aa>,
  • Gdf8<Gdf11aa>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele