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Allele : Tgfb1<tm1(Tgfb3)Kul> transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni

Primary Identifier  MGI:5559039 Allele Type  Targeted
Gene  Tgfb1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The HA-tagged coding sequence for Tgfb3 fused with the sequence of the endogenous gene's latency associated peptide (LAP) and followed by a floxed neomycin resistance cassette replaced exon 2. ELISA confirmed the absence of protein expression in the serum. Western blot analysis confirmed the expression of the HA-tagged protein.
  • mutations:
  • Insertion
  • synonyms:
  • TGF-beta1<Lbeta3>,
  • TGF-beta1<Lbeta3>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories