| Primary Identifier | MGI:5559530 | Allele Type | Targeted |
| Gene | Rtel1 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 34 was replaced with a modified one in which nucleotide substitutions (ATC to GCC) result in the amino acid substitution of alanine for isoleucine at position 1169 (I1169A) and a V5 epitope tag. This mutation abolishes the PCNA-binding site. Cre-mediated recombination removed a floxed splice acceptor, IRES and beta-geo cassette inserted upstream of the modified exon 34. |
